Xiuping Chen Selected Research

germacrone

11/2017	Predicted molecular targets and pathways for germacrone, curdione, and furanodiene in the treatment of breast cancer using a bioinformatics approach.
1/2013	Impact of fixed-dose combination of germacrone, curdione, and furanodiene on breast cancer cell proliferation.
9/2011	Germacrone inhibits the proliferation of breast cancer cell lines by inducing cell cycle arrest and promoting apoptosis.

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Xiuping Chen Research Topics

Disease

54	Neoplasms (Cancer) 01/2024 - 10/2009
18	Lung Neoplasms (Lung Cancer) 01/2024 - 01/2014
16	Inflammation (Inflammations) 12/2023 - 01/2013
16	Breast Neoplasms (Breast Cancer) 09/2023 - 01/2011
12	Neoplasm Metastasis (Metastasis) 09/2023 - 10/2009
11	Atherosclerosis 10/2021 - 10/2006
10	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2019 - 06/2015
6	Necrosis 01/2023 - 01/2017
5	Ischemic Stroke 06/2023 - 11/2015
5	Retinal Neovascularization 01/2022 - 01/2017
5	Insulin Resistance 01/2022 - 06/2012
5	Ovarian Neoplasms (Ovarian Cancer) 06/2017 - 12/2016
5	Cardiovascular Diseases (Cardiovascular Disease) 02/2017 - 11/2008
4	Carcinogenesis 01/2024 - 10/2009
4	Stroke (Strokes) 12/2023 - 05/2017
4	Brain Ischemia (Cerebral Ischemia) 06/2023 - 11/2015
4	Colonic Neoplasms (Colon Cancer) 07/2022 - 01/2017
4	Ulcerative Colitis 01/2021 - 01/2018
4	Body Weight (Weight, Body) 10/2020 - 01/2015
4	Acute Kidney Injury (Acute Renal Failure) 01/2020 - 01/2017
3	Choroidal Neovascularization 02/2024 - 11/2017
3	Infarction (Infarctions) 12/2023 - 01/2019
3	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 06/2023 - 11/2015
3	Hypoxia (Hypoxemia) 01/2023 - 12/2017
3	Mitochondrial Diseases (Mitochondrial Disease) 01/2023 - 12/2018
3	Cardiotoxicity 02/2018 - 01/2018
2	Triple Negative Breast Neoplasms 09/2023 - 05/2022
2	Atherosclerotic Plaque (Atheroma) 04/2023 - 01/2016
2	Wounds and Injuries (Trauma) 12/2022 - 12/2017
2	Weight Loss (Weight Reduction) 01/2021 - 01/2018

Drug/Important Bio-Agent (IBA)

17	Proteins (Proteins, Gene)FDA Link 12/2023 - 01/2011
13	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2024 - 01/2014
8	CytokinesIBA 12/2023 - 11/2008
6	CaspasesIBA 03/2022 - 09/2011
6	ErbB Receptors (EGF Receptor)IBA 08/2020 - 12/2016
6	AdiponectinIBA 12/2016 - 05/2010
5	Oxygen (Dioxygen)IBA 01/2022 - 01/2017
5	Dextran SulfateIBA 01/2022 - 01/2018
5	Tyrosine Kinase InhibitorsIBA 01/2018 - 06/2015
5	oxidized low density lipoproteinIBA 01/2016 - 10/2006
4	Neuroprotective AgentsIBA 01/2023 - 01/2017
4	Biomarkers (Surrogate Marker)IBA 01/2023 - 01/2011
4	neferineIBA 01/2022 - 01/2018
4	LigandsIBA 01/2021 - 10/2006
4	2-methoxy-6-acetyl-7-methyljugloneIBA 01/2020 - 03/2016
4	Nitric Oxide (Nitrogen Monoxide)FDA Link 10/2019 - 03/2016
4	osimertinibIBA 01/2018 - 12/2016
4	furanodieneIBA 11/2017 - 01/2012
4	cucurbitacin BIBA 01/2016 - 01/2014
3	CateninsIBA 02/2024 - 08/2014
3	ginsenoside Rh2IBA 12/2023 - 01/2022
3	NAD (NADH)IBA 01/2023 - 01/2020
3	Oxidoreductases (Dehydrogenase)IBA 01/2023 - 01/2020
3	quinone (benzoquinone)IBA 01/2023 - 01/2020
3	psoralidinIBA 07/2022 - 01/2014
3	Caspase 3 (Caspase-3)IBA 07/2022 - 01/2017
3	Everolimus FDA Link 03/2022 - 01/2017
3	LipopolysaccharidesIBA 01/2022 - 07/2015
3	Small Interfering RNA (siRNA)IBA 09/2021 - 01/2017
3	NitrogenIBA 01/2020 - 06/2012
3	Phosphotransferases (Kinase)IBA 01/2020 - 01/2017
3	Urea (Carbamide)FDA LinkGeneric 01/2020 - 06/2012
3	CalciumIBA 01/2020 - 01/2017
3	Blood Glucose (Blood Sugar)IBA 07/2019 - 06/2012
3	Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric 07/2019 - 05/2011
3	AlkaloidsIBA 01/2019 - 01/2017
3	germacroneIBA 11/2017 - 09/2011
3	LectinsIBA 01/2016 - 09/2010
2	B7-H1 AntigenIBA 12/2023 - 01/2021
2	Doxorubicin (Adriamycin)FDA LinkGeneric 12/2023 - 02/2018
2	LipidsIBA 12/2023 - 01/2016
2	NaphthoquinonesIBA 07/2023 - 03/2016
2	tert-ButylhydroperoxideIBA 06/2023 - 01/2019
2	Interleukin-17 (Interleukin 17)IBA 04/2023 - 01/2023
2	ChloridesIBA 01/2023 - 01/2023
2	IronIBA 01/2023 - 02/2018
2	CollagenIBA 12/2022 - 01/2015
2	Brain-Derived Neurotrophic Factor (BDNF)IBA 07/2022 - 05/2017
2	TOR Serine-Threonine KinasesIBA 03/2022 - 01/2020
2	MTOR InhibitorsIBA 03/2022 - 01/2017
2	RNA (Ribonucleic Acid)IBA 01/2022 - 10/2009
2	InterferonsIBA 01/2022 - 08/2020
2	DNA (Deoxyribonucleic Acid)IBA 01/2022 - 10/2009
2	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 01/2022 - 03/2016
2	InflammasomesIBA 12/2021 - 10/2020
2	nannocystin AxIBA 11/2021 - 01/2021
2	ApolipoproteinsIBA 10/2021 - 01/2016
2	Therapeutic UsesIBA 10/2021 - 08/2020
2	Apolipoproteins E (ApoE)IBA 10/2021 - 01/2016
2	FlavonoidsIBA 10/2021 - 11/2015
2	Interferon-gamma (Interferon, gamma)IBA 09/2021 - 01/2021
2	cryptotanshinoneIBA 10/2020 - 01/2016
2	CreatinineIBA 01/2020 - 08/2017
2	Anti-Inflammatory Agents (Anti-Inflammatories)IBA 01/2020 - 01/2018
2	JNK Mitogen-Activated Protein KinasesIBA 01/2020 - 10/2019

Therapy/Procedure

15	Therapeutics 01/2024 - 10/2009
7	Immunotherapy 12/2023 - 12/2014
5	Drug Therapy (Chemotherapy) 05/2022 - 10/2009
3	Intraperitoneal Injections 05/2022 - 01/2012
2	Intravitreal Injections 01/2021 - 11/2017